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研究开发出癌症新组合疗法 杀死癌细胞有实效

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发表于 2014-2-15 20:45:18 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式

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http://discovery.163.com/14/0214/11/9L1RJ7HP000125LI.html<br><div><p style="margin-top: 26px; margin-bottom: 26px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">加拿大癌症协会称,癌症是加拿大头号疾病,30%的死亡病例均为癌症所致。人们迫切需要新的有效药物,但在短时间内开发出新的抗癌疗法非常困难。渥太华大学的研究人员则另辟蹊径,将目前既存的实验性疗法加以组合来加速对抗癌症恶魔。发表在近期《自然·生物技术》上的科研证据表明,特定组合疗法对杀死癌细胞具有实效。</p><p style="margin-top: 26px; margin-bottom: 26px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">渥太华大学特聘教授、东安大略儿童医院(CHEO)研究所资深科学家罗伯特·科奈卢克期望尽快推动这一新的组合实验疗法进入临床试验。他坚信,新疗法已不再是“是否”有助于癌症患者的问题,而是一个“何时”将成为治疗标准的问题。</p><p style="margin-top: 26px; margin-bottom: 26px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">证据表明,有两种免疫疗法是最具希望的癌症治疗方法。第一种是SMAC拟态疗法,这是一种以凋亡抑制蛋白为基础的针对致癌基因的治疗方法。凋亡抑制蛋白由CHEO在19年前发现。第二种是活病毒疗法,亦称为溶瘤法,这是在渥太华兴起的一个独立研究领域。这两种免疫疗法目前已应用于临床试验,虽然进展令人鼓舞,但两者作为独立疗法,至今尚未表现出实质性的治疗效果。</p><p style="margin-top: 26px; margin-bottom: 26px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">科奈卢克领导的团队发现,将活病毒(或其他非病毒免疫刺激剂)与SMAC模拟物组合在一起,可协同或放大肿瘤杀伤效果,从而克服了单一疗法的局限。组合疗法与具有明显副作用的标准化疗方法完全不同。两种实验性癌症治疗新药组合后,在消灭肿瘤的同时不会对周围的健康组织造成伤害。</p><p style="margin-top: 26px; margin-bottom: 26px; font-size: 14px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">研究人员表示,这两种药物的组合使用或将节约数年的临床开发时间,从而使患者能更快地用上这些药物。研究小组假设,这种组合方式或更适合于特定癌症和具体用途。</p><p style="margin-top: 26px; margin-bottom: 26px; font-size: 14px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;"><strong>总编辑圈点</strong></p><p style="margin-top: 26px; margin-bottom: 26px; font-size: 14px; text-indent: 2em; color: rgb(37, 37, 37); font-family: 宋体, sans-serif; line-height: 24px; text-align: justify;">如果把加拿大科学家的这一成果放在专利的角度下看,它更应该是一种组合、构造上的实用新型,而非原创的发明。毕竟他们没有提出本质上与现有两种疗法完全不同的“第三条路线”。不过在医疗卫生领域,只要能够拯救生命、造福人类,谁还会在意这些呢?更何况它还克服了单一疗法在疗效与副作用等方面的诸多不足。对于这种科研上的“拼凑”,我们只会期望它来得更多。(来源:科技日报 记者 冯卫东)</p></div>
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发表于 2014-2-15 20:47:52 | 只看该作者
中国人放加拿大去,受得了那寒冷的话,多活10-15年问题不大吧
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 楼主| 发表于 2014-2-15 20:53:50 | 只看该作者
回复 2楼tymfnba的帖子

癌症在高纬度地区也一样有啊
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发表于 2014-2-16 00:35:05 | 只看该作者
回复 3楼michaelr的帖子

加拿大污染少,得癌症的几率比在中国低的多吧
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发表于 2014-2-18 11:54:29 | 只看该作者
for victims of the party struggle, the adherents of hate, so not only reprimand Yan Dang, Donglin ** of pain plus punitive expedition. Some have called Zhang Dai &quot;Stone Kui book&quot;, &quot;book though really, hate pro 戴东林,&quot; Zhang Dai explained: &quot;Since her husband Dong Lin Gu Jing Yang (gazetted as) lectures, I curse this country who nominal ninety eight , ...... clique always with the state of calamity. Donglin first cover those things and more real gentleman, who, not without fleeing villain, embraced by key villain &quot;(&quot; Lang Huan anthology &quot;Volume&quot; and Li Yan Weng &quot;) so no support at all. The above analysis captures the political corruption was the main problem is the cut pertinent department. 3, the reason for the fall of the Ming loyalists deep anti Siming Ming Dynasty monarch to investigate the subjugation of responsibilities, is to investigate the actual reasons for the Ming Dynasty, but only focus on finding a monarch or several ministers who are also hard to say profound reflection . In fact the level of awareness adherents also more than that, they conducted a comprehensive study from the broader context,ray ban aviator. As Dai Li as &quot;bandits always pregnant Ling Lu&quot;, from capital missteps, cronies corner stand, imperial lost people, will know soldiers, their pay nuisance, Dali greed residue,ray ban schweiz, either the non-human, kings enrichment, plug the speaker's mouth and ask for the peasant army destroy many other missteps, show the building will be poured next season, a one hundred terminally ill and incurable disadvantages profusion scene. Especially in the first book &quot;preface&quot; to lengthy five thousand words, analyze the reasons for the Ming Dynasty, covered the Chong Zhen Emperor's misconduct, rape inside and outside the minister Yong, policy blunders on the columns of forty-eight, concluded that: &quot;country-induced death, ancestral merit, Timeless personnel all share. &quot;this analysis, and the kind of hate&quot; Compared bandits &quot;who said that&quot; bandits subjugation &quot;hate eunuch who both called&quot; castration vertical subjugation &quot;approach to a comprehensive, objective and much more . Adherents of deep reflection on the causes of the Ming Dynasty also noted that the system in terms of performance problems. Zongxi in the &quot;Ming Yi Dai Fang Lu&quot;, the Ming Dynasty's Bureaucracy, military system, tax system, such as a serious analysis of the imperial examination system, noting its impact on the fall of the Ming Dynasty. For example, &quot;set with papers&amp;quot,ray ban wayfarer; that dynasty, &quot;the emperor to son, the prime minister not to son, the emperor's son is not virtuous, still depends on the prime minister Chuanxian foot remedy phase, the emperor nor lost Yin meaning&quot;; while the Ming Dynasty, &quot;the emperor's son one is not virtuous, no more and as Sage men, and is not intended to son who lost the meaning and call &quot;? Wong believes the prime minister made the abolition of the Ming Dynasty,
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