法国**调查大鼠因食用转基因玉米易患肿瘤的研究

michaelr

<a href="http://www.biodiscover.com/news/research/101841.html">http://www.biodiscover.com/news/research/101841.html</a><br><div><br></div><div><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51); text-align: center;"><img alt="转基因玉米可能让大鼠患上癌症" src="http://api.biodiscover.com/storages/boppakclppcljlpleljldkdlplgkflckbodoeoiobocogodoiocoopcoiohoaojohoopklakhl.png" style="border: 0px none; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: middle; height: 277px; max-width: 100%; width: 444px;"></p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51); text-align: center;">转基因玉米可能让大鼠患上癌症</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">针对一项研究指出转基因玉米可能让大鼠患上癌症，法国**开展了一个关于转基因作物安全性的调查。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">卡昂大学的一个研究小组报告称，大鼠在整个生命周期内被喂食一种常见的转基因玉米后，会患上乳腺癌并严重损害它们的肝脏和肾脏功能。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">尽管之前研究表明，喂食转基因玉米90天对动物没有副作用，而这项研究却被认为首次验证了长时间摄食转基因玉米可带来健康危害。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">不过，独立专家对这项新研究的完整性提出了质疑，声称该法国研究小组具有偏见，并指责该专家成员在数据统计上很可能采取“断章取义”的做法。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">英国没有种植转基因玉米，它们也没有被消费者直接食用，但是每年却进口数十万吨的转基因玉米喂食动物。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">鸡肉、牛肉和猪肉来自于转基因作物喂食的动物，在超市售卖时却没有贴上标签，而专家表示，没有证据表明人类通过食用转基因作物喂养的动物肉会面临任何风险。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);"><strong>大鼠因食用转基因玉米易患肿瘤</strong></p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">这项研究调查了180只大鼠，它们被喂食不同量的抗除草剂型转基因玉米、水剂农达（最畅销的除草剂）以及两种的混合体。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">一个大鼠的正常寿命是 2年，而喂食大鼠2年后，50-80％的雌性大鼠患上至少一处的大肿瘤，而小型对照组却只有30%的患病率。此外，处理组中的雄性大鼠更可能面临肾脏和肝脏的损伤。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">伦敦大学国王学院迈克尔·安东尼奥博士从事这项研究，他说，在所有发表的论文中，这是在转基因作物和农达除草剂对大鼠健康作用领域的一次最彻底研究，结果表明，尤其对于雌性大鼠，有显著数量的肿瘤在早期形成或更具扩散性。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">安东尼奥博士称，由于大鼠经常被用于评估对人类产生的可能毒性影响，这项研究可作为一个具有说服力的指标，我们可以认为转基因玉米和除草剂被食用后可危害人类健康。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);"><strong>反对人士的质疑</strong></p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">不过，英国和国际上一些研究者批评了这一研究论文，声称该研究中，研究人员使用的是本身就易患肿瘤的大鼠，且对照组的范围太小，因此，还不能得出任何结论。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">爱丁堡大学细胞生物学教授Anthony Trewavas称：“在知道对照组90或180只大鼠中的变异度之前，这项结果将变得毫无意义，那本来是应该做的，而这一点毫无疑问地反映了实验人员和资助团体的预定偏差。”</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">伦敦大学国王学院的营养学研究负责人汤姆?桑德斯教授声称则认为论文的作者在数据分析上不合常规。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">在伦敦的新闻发布会上，英国研究人员称，如果这项发现获得更多研究的证实，孟山度公司开发的转基因玉米和农达除草剂应该在市场上叫停。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">在论文发表在食品和化学品毒理学杂志之后，法国部长要求国家卫生安全机构（ANSES）对这项研究进行调查。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">根据ANSES的意见，法国**将敦促欧洲当局采取一切必要措施对人类和动物的健康进行保护，包括紧急叫停欧盟对转基因作物的进口。</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);"><img alt="" src="http://api.biodiscover.com/storages/coppglllppcljlpleljldkdlplgkflckbodoeoeodoaohogogofoopboeofojoeofoboopklakhl.png" style="border: 0px none; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: middle; height: 36px; max-width: 100%; width: 630px;"></p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);"><img src="http://api.biodiscover.com/storages/ikppclfoppcljlpleljldkdlplgkflckbodoeoiobodoeodocoeoopgojoaofogoboboophljlgl.png" style="margin-right: 10px; border: 0px none; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: middle; height: 174px; max-width: 100%; float: left; width: 130px;"><strong>Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize</strong></p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);">Emilie Claira,&nbsp;&nbsp;&nbsp; Robin Mesnagea,&nbsp;&nbsp;&nbsp; Steeve Gressa,&nbsp;&nbsp;&nbsp; Nicolas Defargea,&nbsp;&nbsp;&nbsp; Manuela Malatestab,&nbsp;&nbsp;&nbsp; Didier Hennequinc,&nbsp;&nbsp;&nbsp; Jo?l Spiroux de Vend?moisa</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51); text-align: justify;">The health effects of a Roundup-tolerant genetically modified maize (from 11% in the diet), cultivated with or without Roundup, and Roundup alone (from 0.1 ppb in water), were studied 2 years in rats. In females, all treated groups died 2–3 times more than controls, and more rapidly. This difference was visible in 3 male groups fed GMOs. All results were hormone and sex dependent, and the pathological profiles were comparable. Females developed large mammary tumors almost always more often than and before controls, the pituitary was the second most disabled organ; the sex hormonal balance was modified by GMO and Roundup treatments. In treated males, liver congestions and necrosis were 2.5–5.5 times higher. This pathology was confirmed by optic and transmission electron microscopy. Marked and severe kidney nephropathies were also generally 1.3–2.3 greater. Males presented 4 times more large palpable tumors than controls which occurred up to 600 days earlier. Biochemistry data confirmed very significant kidney chronic deficiencies; for all treatments and both sexes, 76% of the altered parameters were kidney related. These results can be explained by the non linear endocrine-disrupting effects of Roundup, but also by the overexpression of the transgene in the GMO and its metabolic consequences.</p><p style="margin-bottom: 15px; border: 0px; font-family: 微软雅黑, Arial, sans-serif; font-size: 16px; line-height: 26px; vertical-align: baseline; color: rgb(51, 51, 51);"><strong>文献链接</strong>：<a href="http://www.sciencedirect.com/science/article/pii/S0278691512005637" target="_blank" style="border: 0px; font-family: inherit; font-size: inherit; font-style: inherit; font-variant: inherit; line-height: inherit; vertical-align: baseline; color: rgb(0, 0, 0); text-decoration: none;">Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize</a></p></div>

michaelr

2012年9月就有这个报道了
http://v.ifeng.com/news/tech/201 ... -07e02ed69755.shtml